Advances in the Study of Exosomal miRNAs in Diabetes and Its Complications

Diabetes mellitus is a group of metabolism-related diseases characterized by elevated plasma glucose levels, and the course diabetes closely linked to development diabetes-related complications, which can be life-threatening due poor glycemic control. Exosomes are small vesicles that encapsulate intracellular molecules composed variety bioactive proteins, lipids nucleic acids (including microRNAs, lncRNAs, circ-RNAs), recent studies have increasingly shown miRNAs in exosomes an important mode intercellular intertissued communication play key role progression various diseases. This review presents progress application exosomal type 1 (T1DM), 2 (T2DM), complications.